POC Awardees

Proof of Concept funding has helped enable the formation of startup companies, attract venture and angel funding, and advance applications for SBIR/STTR funding.

Below are the POC awardees and their projects since the program's inception in 2012.

Phase I Awardees

Ramaswamy Kalyanasundaram and Justin Richner
College of Medicine
Project Title: Developing a novel mRNA vaccine for lymphatic filariasis and testing it in cell lines and in a mouse model

John Monaghan
College of Liberal Arts and Sciences
Project Title: Spatial and Temporal Modeling of Aircraft Crash Survivor Behavior

Terry Moore and Dustin Fraidenburg
College of Pharmacy and College of Medicine
Project Title: Non-covalent NRF2 activators for pulmonary arterial hypertension

Sangil Kim
College of Engineering
Project Title: Development of Prototype Pouch Cells for High-Performance, Long-Lasting All-Solid-State Batteries Based on Zwitterionic Polyurethane Electrolytes

Bellur S. Prabhakar
College of Medicine
Project Title: Diabodies to Treat Autoimmune Diseases

Pavel A. Petukhov
College of Pharmacy
Project Title: Novel inhibitors of thioredoxin glutathione reductase (TGR) for the treatment of schistosomiasis

Phase II Awardees

Deepak Shukla
College of Medicine
Project Title: DECON: A New Technology to Treat Herpes

Meenesh R. Singh
College of Engineering
Project Title: Fully automated robotic system for effective screening of drug substance

Phase I

Leslie Aldrich
Department of Liberal Arts and Sciences
Project Title: Optimization and evaluation of an autophagy-selective inhibitor for cancer therapy

Deepak Shukla
College of Medicine
Project Title: DECON: A novel platform for enhanced antiviral drug delivery

Meenesh Singh
College of Engineering
Project Title: Fully automated robotic system for effective polymorph screening of drug substance

Arunkumar Subramanian
College of Engineering
Project Title: IC-compatible, direct deposition of patterned nanostructures using physical vapor deposition techniques

Joe Zhou
College of Medicine
Project Title: Three-dimensional functional MRI (fMRI) in focused brain regions

Phase II

Paul Goldspink
College of Medicine
Project Title: Targeting cardiac troponin I for treatment of cardiac myopathies

Reza Shahbazian-Yassar
College of Engineering
Project Title: Commercially viable coating based on graphene oxide nanosheets for dendrite-free lithium metal batteries

Phase I

Paul Goldspink
College of Medicine
Project Title: Targeting 14-3-3/Troponin I in Cardiomyopathy

Russell Pesavento
College of Dentistry
Project Title: Coated Nanoceria as a Caries Prevention Agent

Justin Richner
College of Medicine
Project Title: Dengue virus mRNA vaccine

Fei Song and Jeffrey Loeb
College of Medicine
Project Title: GlyB4 biologic for neurodegenerative diseases

Alexander Yarin and Youngkwan Song
Colleges of Engineering and Nursing
Project Title: Medical device-related pressure injury prevention pressure-indicating material

Phase I

Ayman Al-Hendy
College of Medicine
Project Title: TLR5: Molecular Bio-Imaging Probe to Differentiate Uterine Fibroids from Sarcoma

Gang Cheng
College of Engineering
Project Title: Commercialization of an Anti-infective Urinary Catheter

Gus Cho
College of Medicine
Project Title: Peptide Treatment of Vascular Occlusion in Thromboinflammatory Disease

Reza Shabazian-Yassar
College of Engineering
Project Title: A Commercially Viable Coating Based on Graphene Oxide Nanosheets for Dendrite-Free Lithium Metal Batteries

Phase II

Bin He
College of Medicine
Project Title: Viral Immunotherapy of Cancer

Sandeep Jain
College of Medicine
Project Title: Immunotherapy of Dye Eye Disease

Sangeetha Madhavan
College of Applied Health Sciences
Project Title: DIG-I-PRIME™ to Enhance Stroke Neurorehabilitation

Ajay Maker
College of Surgery
Project Title: A Novel Single Platform Screening Test for Early Stage Pancreatic Cancer

Phase I

Mark Rosenblatt
College of Medicine
Project Title: Intraocular display projector for corneal blindness

Sangeetha Madhavan
College of Applied Health Sciences
Project Title: SMART ankle-foot motion tracker device for neurorehabilitation

Ajay Maker
College of Medicine
Project Title: A novel single platform screening test for early stage pancreatic cancer

Amit Trivedi and Theja Tulabandhula
College of Engineering
Project Title: Delivering robust, real-time artificial intelligence (AI)

Sandeep Jain
College of Medicine
Project Title: Treatment of citrullination-related eye diseases

Bin He
College of Medicine
Project Title: Oncolytic immunotherapy of cancer

Phase II

Rui Xiong and Gregory Thatcher
College of Pharmacy
Project Title: Novel oral treatment for metastatic ER+ breast cancer

Arnon Lavie
College of Medicine
Project Title: TRAIL-asparaginase fusion protein as a novel pancreatic cancer therapeutic

2017 POC Award Winners

Phase I

Mary Jo LaDu
College of Medicine
Project Title: Novel Mechanistic Biomarker for Alzheimer’s Disease in Human Plasma

Arnon Lavie
College of Medicine
Project Title: TRAIL-Asparaginase fusion protein as a novel pancreatic cancer(PC) therapeutic

Jason McAnany
College of Medicine
Project Title: Apparatus and method for noise-based visual

Besma Smida and Danilo Erricolo
College of Engineering
Project Title: Inherent Self‐interference Cancellation for In‐band Full-duplex Wireless Communications

Rui Xiong and Gregory Thatcher
College of Pharmacy
Project Title: Novel Brain-Penetrable, Oral SERDs for ER+Breast Cancer

Phase II

Kaori Yamada
College of Medicine
Project Title: 23 aa Peptide Derived From Kinesin KIF13B Inhibits Angiogenesis: Novel Therapy for Ischemic Diseases

2016 POC Award Winners

Phase I

Marcelo Bonini
College of Medicine
Project Title: Mito-spyro, a new mitochondrial targeted antioxidant with anti-cancer, anti-arrhythmic and potential anti-diabetic functions

Alan Mancini
College of Pharmacy
Project Title: Formulation of Topical Glyburide for Use in Diabetic Wound Care Treatment (Topical Glyburide for Wound Healing)

Igor Veryovkin
College of Liberal Arts and Sciences
Project Title: Right Angle Ion Mirror-Prism (RAIMP) for High Resolution Mass Spectrometry Imaging

Kaori Yamada
College of Medicine
Project Title: 23 aa Peptide Derived From Kinesin KIF13B Inhibits Angiogenesis: Novel Therapy for Ischemic Diseases

Phase II

Terry Vanden Hoek
College of Medicine
Project Title: Phase II-Novel TAT-peptide Improves Sudden Cardiac Arrest (SCA) Survival

2015 POC Award Winners

Spring 2015

Shiva Shahrara
College of Medicine
Project Title: TLR5: A Novel Treatment Strategy for RA Patients

Shane Phillips
College of Applied Health Sciences
Project Title: Wearable Continuous Cardiovascular Sensor and Algorithm for Healthcare & Rehabilitation

Amin Salehi-Khojin
College of Engineering
Project Title: An Advanced Li-Air Battery Cell for Energy Storage Applications

Steven Ackerman
College of Medicine
Project Title: Peptide Nanoparticle Inhibitor of CCR3-Mediated Eosinophilic Inflammation in Asthma

Fall 2015

Terry Vanden Hoek
College of Medicine
Project Title: Phase I-Novel TAT-peptide Improves Sudden Cardiac Arrest (SCA) Survival

Maria Siemionow
College of Medicine
Project Title: Phase I-Novel Chimeric Cell Therapy for Treatment of Duchenne Muscular Dystrophy

Arnon Lavie
College of Medicine
Project Title: Phase I-Novel L-Asparaginase Cancer Drug: Clone 63

Brian Chaplin
College of Engineering
Project Title: Phase I-Commercialization of Reactive Electrochemical Membranes (REMs)

2014 POC Award Winners

Spring 2014

Brian Kay
College of Liberal Arts and Science
Project Title: High-Throughput Antibody Generation by PExSR

Valerie Dobiesz and Stacie Geller
College of Medicine
Project Title: Obsterical Medical Device for Auto Transfusion in Post-Partum Hemorrhage (PPH)

Sriram Ravindran
College of Dentistry
Project Title: Bioenhanced Implant Surfaces for Improved Osteointegration

Mark Grechanik
College of Engineering
Project Title: Making Cloud Computing Elastic, Cost Effective and Efficient

Bellur Prabhakar
College of Medicine
Project Title: Evaluation of Soluble OX40L-JAG-1 to Treat Type-1 Diabetes

Dieter Klatt
Colleges of Engineering and Medicine
Project Title: Validation of In-Vivo SLIM-MRE

Fall 2014

Sudip Mazumder
College of Engineering
Project Title: Wide-Bandgap Optical Emitter Turn-Off (ETO) Thyristor

Mahshid Amirabadi
College of Engineering
Project Title: High Power Density Power Conversion System

Mary Jo LaDu
College of Medicine
Project Title: Novel Biomarkers for Alzheimer’s Disease in Human Plasma

David Peace
College of Medicine
Project Title: Peptide Targeted Immunotherapy of Prostate Cancer

Anantha Harijith
College of Medicine
Project Title: PF-543, a Novel Drug to Treat Oxidative Lung Injury

Alan Kozikowski
College of Pharmacy
Project Title: Use of 5-HT2c-Agonists in Rett Therapy

2013 POC Award Winners

Spring 2013

Venkat Venkatakrishnan
College of Engineering
Project Title: Security Analysis of Online Enterprise Websites

Amin Salehi-Khojin
College of Engineering
Project Title: Novel Catalysts for Syngas Production by CO2 Reduction

Nadim Mahmud
College of Medicine
Project Title: Expanded Cord Blood as an Off-the-Shelf Bridge Graft to Augment Blood Cell Numbers

John Hetling
Colleges of Engineering and Medicine
Project Title:Detecting Glaucoma Where it Starts

Sandeep Jain
College of Medicine
Project Title: New Drug for Treating Dry Eye Disease – Phase I/II Human Trial

Ying Liu
College of Engineering
Project Title: Scalable Process for Manufacturing Nanoparticles Encapsulating Hydrophobic Compounds

Fall 2013

David Carley
College of Engineering
Project Title: Proof of Concept for Real‐Time Prediction of Driving Performance and Safety

Alexander Aruin
College of Applied Health Sciences
Project Title: Design and Optimization of Gait Performance Enhancing Insole

Shaolin Yang
College of Medicine
Project Title: Two-Dimensional J-Resolved LASER and semi-LASER Spectroscopy

Girish Deshpande
Department of Medicine
Project Title: Bench Testing of SecureTube

Spring 2012

Samuel Dudley
College of Medicine
Project Title: A Blood Test to Differentiate Systolic from Diastolic Heart Failure

Xavier Llor
College of Medicine
Project Title: Development of a Blood Test for Colorectal Cancer Screening Using a miRNA Panel

Hayat Onyuksel
College of Pharmacy
Project Title: A Novel Targeted siRNA Delivery Platform Case Study : Liver Fibrosis

Katherine Warpeha
College of Liberal Arts and Sciences
Project Title: Transformation of Critical Crops to Engineer Improved Stress and Yield Characteristics

Fall 2012

Sohail Murad
College of Engineering
Project Title: Water Desalination by an Electric Field Enhanced Ion-Exchange Process

Mahnaz Shahidi
College of Medicine
Project Title: EyeFlow: A Device to Detect Impaired Cerebral Blood Flow

Farhad Ansari
College of Engineering
Project Title: Crack Sensor

Ramaswamy Kalyanasundaram
College of Medicine
Project Title: Improving the Current Lymphatic Filariasis Disease

Seungpyo Hong
College of Pharmacy
Project Title: Development of Biomimetic Device for Detection of Circulating Tumor Cells

Gregory Thatcher and Debra Tonetti
College of Pharmacy
Project Title: Selective Estrogen Mimic (Sem) Treatment of Tamoxifen-Resistant Breast Cancer